Please see accompanying full accompanying full Prescribing Information including Patient Information. In children 6 months to less than 12 years of age, DUPIXENT should be given by a caregiver. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. ![]() Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. It’s an injection given under the skin (subcutaneous injection). Use DUPIXENT exactly as prescribed by your healthcare provider. ![]() You are encouraged to report negative side effects of prescription drugs to the FDA. Call your doctor for medical advice about side effects. These are not all the possible side effects of DUPIXENT. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. The most common side effects in patients with eczema include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, cold sores in your mouth or on your lips, and high count of a certain white blood cell (eosinophilia). Your healthcare provider may stop DUPIXENT if you develop joint symptoms. Tell your healthcare provider about any new or worsening joint symptoms. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Your healthcare provider may send you to an ophthalmologist for an eye exam if needed. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision, such as blurred vision. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue, or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area. DUPIXENT can cause allergic reactions that can sometimes be severe. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.ĭUPIXENT can cause serious side effects, including: Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.Įspecially tell your healthcare provider if you are taking oral, topical or inhaled corticosteroid medicines or if you have atopic dermatitis and asthma and use an asthma medicine. ![]() It is not known whether DUPIXENT passes into your breast milk. are breastfeeding or plan to breastfeed.To enroll or get more information call 1-87 or go to. A pregnancy registry for women who take DUPIXENT during pregnancy collects information about the health of you and your baby.It is not known whether DUPIXENT will harm your unborn baby. are pregnant or plan to become pregnant.You should not receive a “live vaccine” right before and during treatment with DUPIXENT. are scheduled to receive any vaccinations.Important Safety Information and Indicationĭo not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.īefore using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:
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![]() The sellside should take heart in today’s data, since it had previously not assigned any value to Loxo-305. The plan is to gun for late-stage approval first before challenging covalent BTKs broadly, and to this end a randomised programme going head to head against approved BTK inhibitors is to start next year. It has yet to be determined how much data Lilly needs to take Loxo-305 to regulators. He reckons Loxo-305's only real competitor is ARQ 531, which “has a very narrow therapeutic index and is not really a selective kinase inhibitor I feel confident about our standing relative to that drug”. “A key differentiating feature of Loxo-305, in addition to the fact it doesn’t bind covalently, is that the pharmacology of the drug is excellent there is very high oral exposure,” Jacob Van Naarden, chief operating officer at Lilly’s Loxo division, told Evaluate Vantage. This raises an obvious question: how do patients relapse if not via C481S? Lilly’s hypothesis is that this is due to pharmacology failure. There is no analysis for the C481S mutation here, as it is rare in lymphoma. Saturday’s lymphoma cohort showed a 52% ORR in all-comers and in the 52 post-BTK patients alike. The case for Loxo-305 is broader, however, encompassing mutants and wild-type subjects alike, as well as those who have relapsed for unknown reasons.īacking this are the Ash data: the response rate was 63% in the 139 evaluable CLL patients, 62% in the subset of those who had failed a BTK inhibitor, and 71% in those who had failed specifically via the C481S mutation. This had been the pitch for ARQ 531, which yielded remissions in seven of eight C481S mutants before Merck pulled the acquisition trigger. It now includes 139 evaluable CLL patients, detailed today, while a 56-strong cohort in mantle cell lymphoma was presented on Saturday.Ī key reason for developing non-covalent BTK inhibitors is that patients given the covalent variety like Imbruvica can relapse via the C481S mutation. The Ash results are the first glimpse at Loxo-305’s Bruin trial since a year ago, when the dataset comprised just 13 chronic lymphoblastic leukaemia (CLL) and eight lymphoma subjects. ![]() As a non-covalent BTK inhibitor it now rivals Arqule’s ARQ 531, and investors will be well aware that based on a much smaller dataset Arqule was sold to Merck & Co for $2.7bn. Loxo-305 had been originated by Redx Pharma, but was sold off with no royalty obligation to Loxo for just $40m, before Loxo got bought by Lilly. However, through a bizarre set of circumstances the UK no longer has any stake in Loxo-305 – even though the project was invented in England. Success comes rarely to UK biotech, so when something as momentous as the data just reported at Ash with Loxo-305 happens it deserves to be celebrated. Screen Recording Suite is able to record any activities on PC screen in several modes, including custom region, full screen, around mouse and webcam. Screen Recording Suite is perfect tool for making professional screen recordings or screencasts. To record yourself playing a game or put yourself in the video, just click the webcam icon and Screen Recording Suite instantly switches to picture-in-picture mode. To take a screencast, simply click the red Start button in the top left hand corner and Screen Recording Suite will countdown from 3 to 0. In particular, there are useful profiles setup for Apple, Android and Sony device in Screen Recording Suite which makes exporting for different platforms very easy. A built-in video editor however allows you to crop, trim, convert and compress video and output to different video formats, such as AVI, MKV, MP4, SWF, FLV and 3GP etc. Screen Recording Suite naturally also records from your screen and webcam although it saves files in WMV format which isn't the most convenient file for working with in an external edit suite. It also allows users to insert separate voice-overs, images, videos, transition effects, and background music.Screen Recording Suite records from a number of sources including your own internal audio and external devices such as a microphone or musical instrument. In addition, Cam Pro can record from the webcam and the screen, either simultaneously or separately. The paid version of this software, Cam Pro, can export the video in a 1080p-MP4 format. ![]() It can also remove background noise and apply other sound effects to the audio recording.įree Cam can save the screen capture to your local PC as a 760p-WMV file or upload it directly to YouTube. This simple but well-featured editor allows you to trim out unnecessary portions of the video. All it takes to end the recording session is pressing the Esc key.Īfter recording, you can polish the video using the built-in video editor Free Cam provides. When recording, Free Cam hides the application window from view for a seamless recording session. Nevertheless, the paid version removes these limitations with a lifetime guarantee.ĭownload: Bandicam (Free) | Bandicam Pro ($39.95)įree Cam can record system audio from programs as well as voice-over sounds from any connected microphone. The free version also limits each recording session to ten minutes. Bandicut can split recordings or merge multiple recordings into a single video.īandicam offers a free software version, but it adds a watermark to all recorded videos. The editing is done using Bandicut, a free editing program that can be optionally installed with Bandicam. This software can play, edit, and upload screen recordings to YouTube or Vimeo. ![]() Few other screen recording software can provide this functionality. ![]() Bandicam can also record games and HDMI devices using Direct X.īandicam is unique in the way it records external video devices like smartphones, smart televisions, webcams, and gaming consoles. It can output these videos in various formats, including MP4, AVI, and WEBM. Bandicam is a powerful screen recorder for capturing highly-compressed videos while preserving the original quality. ![]() He took us to the wrong place initially and I could’ve gotten us exactly where we needed to be only being there 8 times in my life. Traveling by bus from Denver to Steamboat Springs usually takes around 4 hours and 11 minutes, but the fastest Greyhound bus can make the trip in 4 hours and 10 minutes. Also, strangely we knew the town of Breck better than the driver who claimed to have lived there already. There is one daily bus from Denver to Steamboat Springs. There are 4 ways to get from Denver (Station) to Steamboat Springs by train, taxi, shuttle, car, plane or bus Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner. And if you’ve been to Breck before you know it doesn’t take an hour or less to get there from the Denver area. To book airport service call Steamboat Central Reservations or call 80. Steamboat Express provides shared service from Hayden or Denver International Airport. So crazy that my 18 month old became very car sick about 20min before getting to Breck. The scenic drive is breathtaking You can get a rental car or take a shuttle from either airport to Steamboat. Rides to and from Hayden Airport, Denver International. He drove crazy and way too fast in the express lines almost all the way to Breck. Servicing Steamboat Springs, Oak Creek, Stagecoach, Clark, Craig, Colorado and surrounding areas. In the wintertime, theres a handy service called Snowstang, which provides 40 days of service to four ski. Our driver drove like a maniac! We all felt unsafe! Our guess is he was in a hurry to pick the next guest since they pushed back our time. There are 5 ways to get from Denver Airport (DEN) to Steamboat Springs by plane, bus, shuttle, train, taxi or car Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner. Bustang buses have Wi-Fi, bathrooms and bike racks. I paid for a black car service not a white transit van. ![]() The car that showed up was not the car I paid for. DO NOT BOOK this car service!!! My family and I travel A LOT and this was the worst we have ever experienced! I was called 1 day before our trip saying our pick up time would be pushed back an hour without any apologies or discount on their part for inconveniencing me and my family. ![]() The beautiful teenager has lustrous silver hair that stops at her upper thighs. She’s a significant heroine in the anime series Clannad and becomes the protagonist for a visual novel titled ‘Tomoyo After ~It’s a Wonderful Life~.’ Known for her headstrong personality, Tomoyo excels in fighting, although she’s not the one who’ll start a fight. If there’s a fight at Hikarizaka Private High School, Tomoyo Sakagami will appear. Despite her appearance, she is kind and caring at heart. Orphelia’s eyes are scarlet red and greatly contrast her white hair. This miasma is unpredictable and can sometimes cause the user harm. Orphelia can corrode whatever her hands touch through a miasma. Now, the 17-year-old Strega, a female that can link mana through flesh and blood, walks around with long white hair and a constant look of despair on her pale face. Orphelia Landlufen (Asterisk War)Īs a young child, Orphelia Landlufen had brown hair however, her brown locks turned white as snow after becoming Hilda Jane Rowlands’ test subject. Let’s see how many of these names are you familiar with? Keep count and let us know in the comments section below! Best Anime Girls With White Hair & Silver Hair (2022) 37. So today, we will rank the best white-haired and silver-haired anime girls. Often, white or silver-haired girls hail from different universes or, maybe, are part-ghost. This article is aimed at refreshing your memories or just satisfying your curiosity about finding anime girls with silver hair and white hair. But not to worry, this is not a competition. Even if you consider yourself a hardcore otaku who has watched all sorts of anime shows, you might come up short while naming white-haired anime girls. ![]() I am sure you can think of some, but not many names will come to your mind. From the top of your head, can you think of anime girls with white or silver hair? ![]() You’ll see characters with bright pink hair, red, green, and the list goes on. While Western cartoons tend to stick to black or brown hair color, anime touches the entire spectrum. In such cases, they usually begin by determining its empirical formula A formula for a compound that consists of the atomic symbol for each component element accompanied by a subscript indicating the relative number of atoms of that element in the compound, reduced to the smallest whole numbers., the relative numbers of atoms of the elements in a compound, reduced to the smallest whole numbers. When chemists synthesize a new compound, they may not yet know its molecular or structural formula. To describe the composition of a chemical compound. ![]() zip file containing this book to use offline, simply click here. You can browse or download additional books there. ![]() More information is available on this project's attribution page.įor more information on the source of this book, or why it is available for free, please see the project's home page. Additionally, per the publisher's request, their name has been removed in some passages. However, the publisher has asked for the customary Creative Commons attribution to the original publisher, authors, title, and book URI to be removed. Normally, the author and publisher would be credited here. ![]() This content was accessible as of December 29, 2012, and it was downloaded then by Andy Schmitz in an effort to preserve the availability of this book. See the license for more details, but that basically means you can share this book as long as you credit the author (but see below), don't make money from it, and do make it available to everyone else under the same terms. This book is licensed under a Creative Commons by-nc-sa 3.0 license. ![]() If you are looking for a platform that is easy to use, has low barriers to entry, and offers a lot of customization, flexibility, and integration options, then you must compare their specifications in detail at the time of demo. Magix Fastcut Plus Edition and Monarch Smart Cut Pro can be used for different purposes and are well-suited for teams with specific needs. Which Is Better? - Magix Fastcut Plus Edition or Monarch Smart Cut Pro However, do check for the hidden price, is any. Industry-specific functionalities will ensure higher efficiency and ROI. ![]() ![]() If you are confused between Magix Fastcut Plus Edition or Monarch Smart Cut Pro, you can also check if the software has customizable modules for your industry. For Media House, Monarch Smart Cut Pro is a better choice. Magix Fastcut Plus Edition is ideal for industries like Media House. ![]() Magix Fastcut Plus Edition or Monarch Smart Cut Pro: Which Is Ideal for Your Industry This will help in reducing the hassle after implementation. While selecting between Magix Fastcut Plus Edition and Monarch Smart Cut Pro, figure out which one of the two is compatible with your devices. While Magix Fastcut Plus Edition supports Web Based deployment Monarch Smart Cut Pro is suitable for On Premises deployment. Comparison Between Magix Fastcut Plus Edition and Monarch Smart Cut Pro In terms of Deployment Type The one which suits your business needs is the best. When you compare Magix Fastcut Plus Edition vs Monarch Smart Cut Pro, look for scalability, customization, ease of use, customer support and other key factors. Monarch Smart Cut Pro is known for functionalities like Complete subscription, Fast MPEG/DV AVI, Blu-ray and DVD authoring and Analog and HDMI input and output. Magix Fastcut Plus Edition includes features like Stability, Solution Highlights, Templates and Video Editing. Let’s discover some of the essential factors that you must consider and decide whether Magix Fastcut Plus Edition or Monarch Smart Cut Pro fits your business.Ĭomparison of Magix Fastcut Plus Edition vs Monarch Smart Cut Pro In terms of Features Let’s have a detailed comparison of Magix Fastcut Plus Edition vs Monarch Smart Cut Pro to find out which one is better. MAGIX Fastcut Plus 2017 Steam Edition will run on PC system with 64-bit systems Microsoft Windows 10 | 8 | 7 and upwards.A Quick Comparison Between Magix Fastcut Plus Edition and Monarch Smart Cut Pro Additionally, the game developers recommend somewhere around 8 GB of RAM in your system. The minimum memory requirement for MAGIX Fastcut Plus 2017 Steam Edition is 4 GB of RAM installed in your computer. In terms of game file size, you will need at least 2 GB of free disk space available. However, the developers recommend a CPU greater or equal to an Intel Core 2 Quad Q9500 to play the game. To play MAGIX Fastcut Plus 2017 Steam Edition you will need a minimum CPU equivalent to an Intel Pentium 4 2.00GHz. But, according to the developers the recommended graphics card is an NVIDIA GeForce 510. Provided that you have at least an NVIDIA GeForce 6100 graphics card you can play the game. Quad-core processor with 2.8 GHz or betterĦ4-bit systems Microsoft Windows 10 | 8 | 7 ![]() These and many other features of our network inventory software will save you a lot of effort and stress during network audits.
![]() Stretch marksĪlmost every pregnant woman will get stretch marks, which are reddish streaks that run down your breasts or belly. Melasma sometimes doesn’t go away, but a dermatologist can treat it with medication after pregnancy. Don’t worry – you won’t be stuck with these changes forever. You can’t totally prevent these conditions, but using a good sunscreen, especially on your face, can help reduce the effects. And the darker your skin tone, the more you may notice these changes. Many women, for example, report much darker freckles or areolas than normal. This increase in pigmentation can affect any area of your body that is more pigmented. Nearly 75 percent of pregnant women will have the mask of pregnancy, and 90 percent will notice linea nigra. If you experience either of these, you’re not alone. Linea nigra is a dark line that can form between your belly button and pubic area during pregnancy. Melasma, also known as the “mask of pregnancy,” causes dark splotches to appear on your face, often on the nose and cheeks. ‘Mask of pregnancy’ and linea nigraīoth of these benign conditions are the result of increased pigmentation caused by a surge of pregnancy hormones. We’ll also discuss one serious condition of which to be aware. Let’s take a look as some of the most common skin problems that pop up during pregnancy and how to manage them. Fortunately, while annoying, most of these conditions are harmless and will subside after you give birth. Pregnancy can bring about many strange symptoms, and your skin is not immune to the hormone changes you’re experiencing. Or perhaps you’re itchy from a rash that has sprung up around the stretch marks on your belly. Maybe dark splotches have popped up on your face. And this condition has a predilection for areas that are covered.You’re well into pregnancy, so where’s that “pregnancy glow” you’ve heard about? Instead of bright, radiant-looking skin, you might look more like a pimple-faced teenager. Cutaneous t-cell lymphoma (CTL) is actually a type of skin cancer, relating to abnormal immune cells called lymphocytes. They call it eczema, they call it dry skin, and it's not,” says Adam Friedman, MD, a professor of dermatology at GW School of Medicine and Health Sciences. If you are currently dealing with a rear-end rash, here are some of the most common rashes and how they may appear depending on your skin tone, so you know exactly what to look for, plus treatments that can ease your symptoms. I know that there are so many efforts ongoing to address that, but unfortunately, we are not there." "The result of that is either under-diagnosis, misdiagnosis, or taking a long time to diagnose for our patients of color. ![]() "When the images in the textbooks and images in the lectures are not diverse and are not really reflective of society and what you will see in the real world, then that bias is ingrained in medical education," says Caroline Robinson, MD, the founder and CEO of Tone Dermatology in Chicago. And pictures of rashes in medical textbooks often feature white models. To make the situation even more complicated, different skin conditions look different on light skin compared to darker skin colors. Sometimes a minor bump could just be a simple pimple, but you may not know what you’re dealing with when the irritation is bigger, redder, and even painful. ![]() ICYMI, a butt rash can happen to adults too, not just babies. Rashes are itchy and annoying, but they bring on a whole new level of discomfort when they appear on your butt. ![]() To avoid maxing out your Lightroom cloud storage space, try culling with Narrative Select first. Lightroom can be a great option for photographers who are on the go and use multiple devices to edit. Once you are done culling and have selected your best images, you can quickly and easily “ship” them to Lightroom. As a result, you are viewing 20-30% less images per shoot. This means there is no more time spent second-guessing! Image assessments allow you to quickly identify the worst images from your shoot and then hide them. Focus assessments allow you to quickly identify if your subjects are in or out of focus. The eye assessments allow you to quickly identify if your subject’s eyes are open or closed. Select also has a heap of features that make your culling process faster. Narrative Select is FAST! There are no wait times when importing or navigating through your photos, and no low res images or loading bars. One way to avoid culling in Lightroom is by using an efficient culling tool, such as Narrative Select. Using Lightroom to cull photos is not only much slower, but it will also quickly fill up precious cloud storage. However, if having the ability to sync images across devices is a huge benefit for you, culling before you import into Lightroom is a MUST.Ĭulling is the process of going through all the images from a shoot and choosing the best ones to edit. For some people, Lightroom still won’t be as economically viable as Lightroom Classic. To continue working in Lightroom, you essentially need to be much more ruthless with the images you keep. You can upgrade your quota through Adobe Creative Cloud, but it can get expensive fast.Ĭulling your photos before importing them into Lightroom ![]() On the Adobe Photography Plan you are only given a 20GB quota of storage. If you’re a wedding photographer working with 1000s of full resolution image files, you can easily max out your storage. Since Lightroom utilizes the cloud, which allows images to sync between devices, there is the issue of limited storage. This can be a huge benefit to people who work on the go and use multiple devices. ![]() The main benefit to Lightroom is that because your images are stored in the cloud, they will appear on any device where you have Lightroom downloaded. Lightroom is a cloud-based app that stores your images in the cloud. Lightroom Classic is a desktop application that uses images stored locally or on an external hard drive/SSD. The difference between Lightroom and Lightroom Classicīefore we dive into optimising Lightroom cloud storage, it’s important to explain the difference between Lightroom and Lightroom Classic.īoth types of software are used for organising and editing photos, but they don’t think the same way. This blog will outline the benefits of Lightroom and how culling images prior to import can save you from maxing out your Lightroom cloud storage. What isn't discussed as much is how fast your Lightroom storage can fill up and how to prevent it. How to avoid maxing out your Lightroom cloud storageĪ big discussion in the photography community is about Lightroom (formerly Lightroom CC) and it’s benefits compared to Lightroom Classic. |
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